What is Semax used for in research?

Semax is supplied strictly as a research reference material for qualified in vitro and analytical laboratory workflows. It is not intended for human or veterinary use, diagnosis, or therapeutic application.

How is Semax purity verified?

Batches are accompanied by specification documentation and Certificate of Analysis (COA) data where available. Review the product page and request COA details before incorporating material into regulated studies.

How should Semax be stored?

Store lyophilized material according to the label and COA. After reconstitution, follow your institutional SOP for temperature, light exposure, and working-solution stability.

Who can purchase Semax from Science Based Peptides?

Catalog items are sold to qualified researchers and laboratories for research use only. Buyers must confirm age and research-use eligibility before checkout.

Does Science Based Peptides ship Semax in the USA?

Yes — we fulfill research peptide orders to qualified customers in the United States subject to product availability and our shipping policies listed at checkout.

Semax research peptide - Science Based Peptides

For laboratory research use only. Not for human consumption.

Neuropeptide Research

Semax Peptide For Sale

Name: Semax
Brand: Science Based Peptides
SKU: semax
Price: 29.99 USD
Availability: InStock

ACTH-derived peptide analog for neuropharmacology research.

Semax (ACTH 4-7 Pro8-Gly9-Pro10)

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$29.99

Type

Research Peptide

What is Semax?

Semax (Semax (ACTH 4-7 Pro8-Gly9-Pro10)) is offered as a research reference material for qualified analytical and in vitro laboratory workflows. ACTH-derived synthetic peptide analog for neuropharmacology and neuropeptide pathway research in controlled animal models. For laboratory research use only. Not for human consumption.

How it Works

In research settings, Semax is used to probe defined biological pathways under controlled laboratory conditions. Mechanistic studies typically combine receptor or cell-based assays with analytical verification of peptide identity and integrity.

Purity & Testing

99% minimum purity (per specification / COA for the active batch). Each lot is tied to batch documentation so researchers can align material received with COA and specification records before use in regulated workflows. Request a COA from this page if you need documentation prior to purchase.

Storage & Handling

Store lyophilized material per label and COA. Solvent selection and working-solution preparation must follow institutional laboratory SOPs.

Research Overview

ACTH-derived peptide analog for neuropharmacology research.

Specifications

Compound	Semax (ACTH 4-7 Pro8-Gly9-Pro10)
Presentation	10MG
purity	High Purity
storage	Refrigerated (2-8C recommended)
type	Sterile Water
volume	10MG
CAS	80714-61-0
Purity	99%
Catalog reference period	14 days

Sources & References

Peer-reviewed research

Neuroscience and Behavioral Physiology

Semax — an analog of ACTH(4-10): biological activity and clinical applications

1997 · DOI: 10.1007/BF02462874 · PMID: 9223891

Ashmarin IP, Nezavibatko VN, Levitskaya NG, et al.

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Bulletin of Experimental Biology and Medicine

Effects of Semax and its Pro-Gly-Pro fragment on regional cerebral blood flow

2007 · DOI: 10.1007/s10517-007-0273-x · PMID: 17549321

Eremin KO, Kudrin VS, Saransaari P, et al.

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Journal of Neurological Sciences

Semax in the treatment of acute ischemic stroke

2011 · DOI: 10.1016/j.jns.2011.06.040 · PMID: 21807377

Gusev EI, Skvortsova VI, Miasoedov NF, et al.

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British journal of pharmacology

Semax peptide targets the μ opioid receptor gene Oprm1 to promote deubiquitination and functional recovery after spinal cord injury in female mice

2025 · DOI: 10.1111/bph.70122 · PMID: 40692165

Liu R, Chen Y, Huang H, et al.

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ACS chemical neuroscience

Semax, a Synthetic Regulatory Peptide, Affects Copper-Induced Abeta Aggregation and Amyloid Formation in Artificial Membrane Models

2022 · DOI: 10.1021/acschemneuro.1c00707 · PMID: 35080861

Sciacca MFM, Naletova I, Giuffrida ML, et al.

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Bioinorganic chemistry and applications

Semax, a Copper Chelator Peptide, Decreases the Cu(II)-Catalyzed ROS Production and Cytotoxicity of aβ by Metal Ion Stripping and Redox Silencing

2025 · DOI: 10.1155/bca/4226220 · PMID: 40496623

Tomasello MF, Di Rosa MC, Naletova I, et al.

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BMC genomics

The peptide semax affects the expression of genes related to the immune and vascular systems in rat brain focal ischemia: genome-wide transcriptional analysis

2014 · DOI: 10.1186/1471-2164-15-228 · PMID: 24661604

Medvedeva EV, Dmitrieva VG, Povarova OV, et al.

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Acta naturae

The Potential of the Peptide Drug Semax and Its Derivative for Correcting Pathological Impairments in the Animal Model of Alzheimer's Disease

2025 · DOI: 10.32607/actanaturae.27808 · PMID: 41479572

Radchenko AI, Kuzubova EV, Apostol AA, et al.

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International journal of molecular sciences

Brain Protein Expression Profile Confirms the Protective Effect of the ACTH((4-7))PGP Peptide (Semax) in a Rat Model of Cerebral Ischemia-Reperfusion

2021 · DOI: 10.3390/ijms22126179 · PMID: 34201112

Sudarkina OY, Filippenkov IB, Stavchansky VV, et al.

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Molekuliarnaia biologiia

[The Peptide Drug ACTH(4-7)PGP (Semax) Suppresses mRNA Transcripts Encoding Proinflammatory Mediators Induced by Reversible Ischemia of the Rat Brain]

2021 · DOI: 10.31857/S0026898421010043 · PMID: 34097675

Dergunova LV, Dmitrieva VG, Filippenkov IB, et al.

View Source

Frequently Asked Questions

What is Semax used for in research?: Semax is supplied strictly as a research reference material for qualified in vitro and analytical laboratory workflows. It is not intended for human or veterinary use, diagnosis, or therapeutic application.
How is Semax purity verified?: Batches are accompanied by specification documentation and Certificate of Analysis (COA) data where available. Review the product page and request COA details before incorporating material into regulated studies.
How should Semax be stored?: Store lyophilized material according to the label and COA. After reconstitution, follow your institutional SOP for temperature, light exposure, and working-solution stability.
Who can purchase Semax from Science Based Peptides?: Catalog items are sold to qualified researchers and laboratories for research use only. Buyers must confirm age and research-use eligibility before checkout.
Does Science Based Peptides ship Semax in the USA?: Yes — we fulfill research peptide orders to qualified customers in the United States subject to product availability and our shipping policies listed at checkout.